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Molecular mechanisms of autophagy decline during aging

However, a high level of ROS inhibits the occurrence and development of tumors by inducing apoptosis of tumor cells because of their toxic effects [40]

According to what is stated above, Nrf2 inhibits ferroptosis through multiple pathways

Curcumin reverses resistance to gemcitabine through various mechanisms such as inhibiting drug efflux pumps, regulating signaling pathways (such as PI3K/AKT), and inducing specific modes of death (such as ferroptosis) (Namwa et al., 2025

Dolastatin 10 affects CD95/fas, XIAP and Bcl-2 family proteins and is dependent on baseline MDR-1 levels in primary AML: Correlative study in a phase I trial